Importance Of The E-tegrity Test

Unexplained infertility can cause anxiety and other concerns for a woman who is trying to become pregnant. An endometrial biopsy and the E-tegrity Test can help provide treatment options. By testing a womans uterine lining, the reason for fertility problems can be identified so that a successful plan of action can be determined by the patient and her doctor. The E-tegrity Test uses an endometrial biopsy to determine the presence of Beta-3 integrin, a protein with glue-like properties that is needed for the fertilized egg to be implanted as part of the in vitro fertilization process.

Studies have shown that women with endometriosis lack Beta-3 integrin. Endometriosis is when tissue from the lining of the womb or uterus grows in other areas of the body. Although the causes of this condition are not entirely understood, it is thought that problems with menstrual flow are a major factor. A diagnosis for the condition can be made using a pelvic exam or an ultrasound. Untreated, this condition can lead to pregnancy problems. Endometriosis treatment options are related to the various endometriosis stages. Treatment options include exercise, medication, and surgery.


Since there is no infertility cure, women need to work closely with their physician to determine the best infertility treatment options. An expensive in vitro fertilization procedure may fail if the Beta-3 integrin is not present. As part of a female infertility treatment process, the E-tegrity Test, performed with an endometrial biopsy can help ensure that a previously unexplained infertility condition is resolved and a successful outcome achieved.